The manufacturer suggests that a Reusable Nebulizer Cup be replaced at least every 6 months. Depending upon the frequency of use, medication used and cleaning/sterilization method used, more frequent replacement may be necessary to optimize nebulizer performance.

The performance of the nebulizer cup will deteriorate with time and use. If the nebulizer treatment time is becoming prolonged, this is typically an indication that the nebulizer cup should be replaced.